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N-Terminal bromodomain of Human BRD2 with I-BET726 (GSK1324726A)

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4uyf
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N-Terminal bromodomain of Human BRD2 with I-BET726 (GSK1324726A) Descriptor: 1,2-ETHANEDIOL, 4-[(2S,4R)-1-acetyl-4-[(4-chlorophenyl)amino]-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl]benzoic acid, BROMODOMAIN-CONTAINING PROTEIN 2, ... Authors: Chung, C, Bamborough, P, Gosmini, R. Deposit date: 2014-08-31 Release date: 2014-10-08 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The Discovery of I-Bet726 (Gsk1324726A), a Potent Tetrahydroquinoline Apoa1 Up-Regulator and Selective Bet Bromodomain Inhibitor. J.Med.Chem., 57, 2014
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2014-08-31
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