Gene expression analysis in canine discoid/chronic lupus erythematosus, mucocutaneous lupus erythematosus and pyoderma. Gene expression analysis in canine discoid/chronic lupus erythematosus, mucocutaneous lupus erythematosus and pyoderma

We performed a comparative immunology case study of client-owned dogs to determine if immune and skin gene expression profiles in spontaneous canine cutaneous lupus erythematosus mirror those observed in human cutaneous lupus. Overall design: Gene expression was analyzed using 160 custom Nanostring probes to analyze 7 canines with DLE, 1 canine with CCLE, 1 canine with MLE and 1 canine with pyoderma compared to 5 healthy controls (leg margin excisions). UPDATE: [09-11-2024] For Sample GSM4869949, the title was changed from "Skin_biopsy_DICLE_case1" to "Skin_biopsy_Control/Pyoderma_case3", and the disease status was changed from "DICLE" to "Control/Pyoderma".