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SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes.

NIAID Data Ecosystem2026-05-01 收录

果蝇生殖细胞发育

SUMO化修饰与基因沉默

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE241375 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-12-08

果蝇生殖细胞发育

RNAi筛选

In Drosophila melanogaster, primordial germ cells are specified at the posterior pole of the very early embryo. This process is regulated by the posterior localized germ plasm that contains a large nu

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Integrative analysis unveils new functions for the Drosophila Cutoff protein in non-coding RNA biogenesis and gene regulation

非编码RNA调控

果蝇生殖细胞发育

Piwi-Interacting RNAs (piRNAs) are central components of the piRNA pathway, which directs transposon silencing and guarantees genome integrity in the germ cells of several metazoans. In Drosophila, pi

NIAID Data Ecosystem50

Trajectory Mapping of the Early Drosophila Germline Reveals Controls of Zygotic Activation and Sex Differentiation. Trajectory Mapping of the Early Drosophila Germline Reveals Controls of Zygotic Activation and Sex Differentiation

果蝇生殖细胞发育

单细胞转录组学

We report single-cell RNA-sequencing data for sexed D. melanogaster germ cells from 0-8h embryos. We find in this time window that the transcriptome of male and female germ cells diverge and this coin

NIAID Data Ecosystem40

CIL:13739

果蝇生殖细胞发育

蛋白质亚细胞定位

Boi (green) localizes predominantly to apical cells in Drosophila wild-type germaria but not in boi[e] mutant germaria (CIL#13740). Germ cells are identified using anti-Vasa (blue). Image is Fig 2B in

Figshare2013-03-08 更新60

From embryo to adult: piRNA-mediated silencing throughout germline development in Drosophila. piRNA during germline development in Drosophila

piRNA介导的沉默

果蝇生殖细胞发育

In metazoan germ cells, transposable element activity is repressed by small noncoding PIWI-associated RNAs (piRNAs). Numerous studies in Drosophila have elucidated the mechanism of this repression in

NIAID Data Ecosystem50

SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes.

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