PTENα/β paradoxically promote carcinogenesis through WDR5-H3K4me3 axis

NIAID Data Ecosystem2026-03-11 收录

癌症表观遗传学

分子致癌机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE126984 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2019-11-14

Control ChIP-seq from HCT116 (ENCSR936ENS)

染色质免疫沉淀测序

癌症表观遗传学

For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf https://www.e

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Prevention of chromatin destabilization by FACT is crucial for malignant transformation. Prevention of chromatin destabilization by FACT is crucial for malignant transformation

癌症表观遗传学

染色质动力学

Histone chaperone FACT is commonly expressed and essential for the viability of transformed but not normal cells and its expression levels correlate with poor prognosis in cancer patients. FACT binds

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Summary of OPCML methylation in cell lines and primary tumors.

癌症表观遗传学

DNA甲基化分析

Summary of OPCML methylation in cell lines and primary tumors.

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Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients

癌症表观遗传学

药物耐药性

Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic

DataONE2020-06-24 更新60

Dynamic imbalance between cancer cell subpopulations induced by Transforming Growth Factor Beta (TGF-β) is associated with a DNA methylome switch [methylation]

癌症表观遗传学

癌细胞异质性

Distinct subpopulations of neoplastic cells within tumors, including hepatocellular carcinoma (HCC), display pronounced ability to initiate new tumors and induce metastasis. Recent evidence suggests t

NIAID Data Ecosystem40

PTENα/β paradoxically promote carcinogenesis through WDR5-H3K4me3 axis

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