Inhibition of histone readers bromodomain extra-terminal proteins alleviates scleroderma fibrosis. Inhibition of histone readers bromodomain extra-terminal proteins alleviates scleroderma fibrosis

We assessed transcriptomic changes in fibroblasts isolated from skin biopsies from diffuse cutaneous scleroderma patients before and after BET inhibitor JQ1 treatment Overall design: RNA-seq analysis of fibroblasts in diffuse cutaneous systemic sclerosis patients after JQ1 treatment