RAGE rs184003 rs2070600 genotyping

Background: The development of coronary artery disease (CAD) is the result of complex interactions between environmental and genetic factors. While the former is well known, the genetic factors that predispose individuals to the development of CAD are still under investigation. The aim of our study was to investigate whether single nucleotide substitution polymorphisms (SNPs), rs2070600 G/A and rs184003 G/T, in the gene encoding the receptor for advanced glycation end products (RAGE) may determine predisposition to CAD in the Polish population. Methods: Two RAGE SNPs were genotyped in 336 patients with a history of acute coronary syndrome (ACS): 175