官方服务:
资源简介:
p65 mediated Mettl3 and 14 transactivation and m6A-dependent TGFB1 translation aggravates fibrosis progression in NASH
应用场景:
创建时间:
2021-01-19
相关数据集
Monocyte-derived Macrophages. Monocyte-derived Macrophages
Chronic liver diseases as non-alcoholic steatohepatitis (NASH)-induced cirrhosis are characterized by an increasing accumulation of stressed, damaged, or dying hepatocytes. Hepatocyte damage triggers
NIAID Data Ecosystem50
Renal fibrosis due to multiple cisplatin treatment is exacerbated by kinin B1 receptor antagonism
Cisplatin is a widely used chemotherapeutic drug, but its side effects are a major limiting factor. Nephrotoxicity occurs in one third of patients undergoing cisplatin treatment. The acute tubular inj
NIAID Data Ecosystem30
Different effects of rat interferon alpha, beta and gamma on rat hepatic stellate cell proliferation and activation
BACKGROUND: Liver fibrosis is the common sequel of chronic liver diseases. Recent studies have identified hepatic stellate cells as the primary cell type mediating hepatic fibrogenesis. It has been de
PubMed Central2002-04-08 更新20
Data_Sheet_1_Pyruvate kinase M2 modification by a lipid peroxidation byproduct acrolein contributes to kidney fibrosis.docx
Renal fibrosis is a hallmark of diabetic nephropathy (DN) and is characterized by an epithelial-to-mesenchymal transition (EMT) program and aberrant glycolysis. The underlying mechanisms of renal fibr
NIAID Data Ecosystem40
Transthyretin alters cardiac fibroblast structure, function and inflammatory gene expression.
Age-related wild type transthyretin amyloidosis (wtATTR) is characterized by systemic deposition of amyloidogenic fibrils of misfolded transthyretin (TTR) in the connective tissue of many organs. In t
Alliance of Genome Resources20



