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Cytosine deaminase base editing to restore COL7A1 in dystrophic epidermolysis bullosa human:murine skin model.

NIAID Data Ecosystem2026-05-01 收录

基因编辑治疗

遗传性皮肤病

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP410218 数据链接链接失效反馈

官方服务：

资源简介：

NGS off-target analysis following base editing of COL7 ex3 in RDEB human patient cells

应用场景：

创建时间：

2023-03-31

基因编辑治疗

免疫缺陷疾病

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem100

Molecular assessment of familial skin fibrosis

遗传性皮肤病

分子病理机制

This project is about exploring the inheritance of fibrotic lumps within the skin. We have identified two pedigrees with autosomal dominant inheritance pattern indicating a mendelian segregation in so

NIAID Data Ecosystem50

Base editor mediated correction of a tau mutation rescues cognitive decline in a mouse model of Alzheimers disease. Homo Sapiens

基因编辑治疗

阿尔茨海默病模型

Low sequence reads

NIAID Data Ecosystem40

Diverse clinical and genetic characteristics of six cases of inherited epidermolysis bullosa (IEB)

遗传性皮肤病

基因测序

Background: Inherited epidermolysis bullosa (IEB) represents a group of rare genetic dermatoses comprising a wide spectrum of phenotypes ranging from severe cutaneous and extracutaneo

DataCite Commons2022-09-06 更新80

Efficient in vivo Genome Editing Prevents Hypertrophic Cardiomyopathy in Mice [Amplified_cDNA]. Efficient in vivo Genome Editing Prevents Hypertrophic Cardiomyopathy in Mice [Amplified_cDNA]

基因编辑治疗

肥厚型心肌病动物模型

Dominant pathogenic variants encoding amino acid substitutions in cardiac myosin heavy chain cause hypertrophic cardiomyopathy (HCM), a currently incurable disorder that increases risk for stroke, hea

NIAID Data Ecosystem50

Cytosine deaminase base editing to restore COL7A1 in dystrophic epidermolysis bullosa human:murine skin model.

资源简介：

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