Expression of STAT5 upregulated genes

Interleukin-7 (IL7) stimulation upregulates expression of the transcripts and proteins encoding Cytokine-inducible SH2-containing protein (CISH), Suppressor of cytokine signaling 1 (SOCS1) and Suppressor of cytokine signaling 2 (SOCS2) in CD8+ T cells (Ghazawi et al. 2016).<br>This is a black-box event since details of the mechanism of transcription and translation are omitted.

白介素-7（IL7）刺激上调了编码Cytokine诱导的SH2结构域蛋白（CISH）、细胞因子信号传导抑制因子1（SOCS1）和细胞因子信号传导抑制因子2（SOCS2）的mRNA和蛋白质的表达，此过程在CD8+ T细胞中发生（Ghazawi等人，2016年）。此事件为黑盒事件，因为转录和翻译机制的细节被省略。