Type I interferon (IFN) response in USP18 knockout in THP-1 AML cells [ChIP-seq]
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下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP303134
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资源简介：
Type I IFN induces IFN stimulated genes (ISGs) and exert varieties of immunomoduratory functions. However, it is not well characterized how ISGs are regulated by negative regulators of IFN signaling. Here, we analyzed the chromatin activity using H3K27Ac ChIP when combined with depletion of USP18, one of major negative regulators for IFN signaling. Overall design: ChIP-sequencing of control and USP18KO THP-1 cells with or without IFN treatment for 6 hours. For ChIP-sequencing, 2 biological replicates were prepared for each condition.
创建时间：
2023-02-09
