Rh-30 micro array data, knockdown of PAX3-FOXO1 and B7-H3. Rh-30 micro array data, knockdown of PAX3-FOXO1 and B7-H3

To investigate the effect of PAX3-FOXO1 and B7-H3 in rhabdomyosarcoma, Rh-30 (PAX3-FOXO1 positive rhabdomyosarcoma cell line) was transfected by siPAX3-FOXO1 or siB7-H3. After knockdown, total RNA was extracted and analyzed. As a result, some genes and pathways, such as chemotaxis, differentiation, and INF-gamma production were comonnly effected by PAX3-FOXO1 and B7-H3. Overall design: Rh-30 was transfected by siControl or siPAX3-FOXO1 or siB7-H3. After 24 hours, total RNA was extracted and analyzed. There are 3 samples. Rh-30 siControl was compered by Rh-30 siPAX3-FOXO1 and/or Rh-30 siB7-H3