Active ALK binds Frs2
收藏reactome.org2025-03-22 收录
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Rat Frs2 co-immunoprecipitates with human ALK when co-expressed in HEK203 cells. Interaction is dependent on the tyrosine kinase activity of ALK, although a precise binding site for FRS2 has not been identified (Degoutin et al, 2007).
大鼠Frs2与人类ALK在HEK203细胞中共表达时,发生免疫共沉淀。该相互作用依赖于ALK的酪氨酸激酶活性,尽管尚未确定FRS2的精确结合位点(Degoutin等,2007年)。
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