Crystal structure of mutant estrogen receptor alpha Y537S in complex with CO9
收藏Protein Data Bank Japan2024-10-16 更新2026-04-19 收录
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Crystal structure of mutant estrogen receptor alpha Y537S in complex with CO9 Descriptor: (~{Z})-4-[2-[4-[[2-(4-hydroxyphenyl)-6-oxidanyl-1-benzothiophen-3-yl]oxy]phenoxy]ethylamino]-~{N},~{N}-dimethyl-but-2-enamide, Estrogen receptor Authors: Xiao, Y, Lv, Y. Deposit date: 2022-01-19 Release date: 2023-01-25 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: X-ray crystallography study and optimization of novel benzothiophene analogs as potent selective estrogen receptor covalent antagonists (SERCAs) with improved potency and safety profiles. Bioorg.Chem., 141, 2023
创建时间：
2022-01-19
