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Next Generation Sequencing Facilitates Quantitative Analysis of the effects of CB2 on lung ILC2 Transcriptomes

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP346816
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CB2 signaling supports secretion of ILC2 effector cytokines ex vivo. Increased ILC2 activation leads to the development of airway hyperreactiviy and lung inflammation. Targeting CB2 signaling may therefore represent a novel therapeutic target to treat asthma. Overall design: mRNA profiles of sorted mouse lung ILC2s from either WT or CB2 KO mcie were generated by deep sequencing, in triplicate, using a NextSeq 500 (Illumina) system.
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2021-11-20
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