Co-crystal structure of human transthyretin conjugated to the stilbene substructure derived from reaction with the fluorogenic covalent kinetic stabilizer A2
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Co-crystal structure of human transthyretin conjugated to the stilbene substructure derived from reaction with the fluorogenic covalent kinetic stabilizer A2 Descriptor: S-(4-fluorophenyl) 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzenecarbothioate, Transthyretin Authors: Yan, N.L, Nugroho, K, Kline, G.M, Basanta, B, Lander, G.C, Wilson, I.A, Kelly, J.W. Deposit date: 2023-09-11 Release date: 2025-03-05 Last modified: 2025-05-28 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The conformational landscape of human transthyretin revealed by cryo-EM. Nat.Struct.Mol.Biol., 32, 2025
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2023-09-11
