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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
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创建时间：
2023-06-11
相关数据集
Global Histone H3 lysine 4 trimethylation (H3K4me3) landscape changes in response to TGF-β1. Global Histone H3 lysine 4 trimethylation (H3K4me3) landscape changes in response to TGF-β1
We performed Chromatin-Immunoprecipitation followed by Next-Generation Sequencing (ChIP-Seq) in PC-3 Cells stimulated with TGF-β1 for different duration. We used anti-H3K4me3 antibody to immunoprecipi
NIAID Data Ecosystem60
Analysis of epithelial and mesenchymal populations in tumor-derived cell lines by scRNA-seq
This experiment includes single cell transcriptome data for the epithelial and mesenchymal populations isolated from a pancreatic tumor induced in GEM mouse.
NIAID Data Ecosystem30
Knockdown of Akt1/2 by CRISPR/Cas9 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo. Knockdown of Akt1/2 by CRISPR/Cas9 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo
Our findings will initially map out the downstream signal pathways of Akt and AR mutual feedback to regulate CaP metastasis through the study of these scientific assumptions, which will provide target
NIAID Data Ecosystem10
Next generation sequencing showing miRNA profiles of exosomes derived from DHT-treated CAFs and matched ETOH-treated CAFs
Background: Androgen deprivation therapy (ADT) is the backbone of therapy for advanced prostate cancer (PCa). Despite the good initial response, castration resistance and metastatic progression will i
NIAID Data Ecosystem60
The evolutionary steps from primary to metastatic prostate cancer are largely uncharted, and the ability to use DNA present in body fluids as correlates of aggregate metastatic status is under-examined. We reconstructed phylogenies in ten prostate cancer patients with fatal disease using deep targeted sequencing of the prostate, adjacent and distant organs, as well as plasma, serum, and cerebrospinal fluid at various time points. A total of 163 samples are studied.
The evolutionary steps from primary tumor to metastasis in prostate cancer are largely uncharted, and the ability to use serum, plasma, and cerebrospinal fluid as a correlate of aggregate metastatic t
NIAID Data Ecosystem10
