Common structure-disruptive SNPs within IBD and T1D loci-associated lncRNAs.

Four SNPs common between an IBD and T1D loci-associated antisense lncRNA were in close proximity of a protein coding gene HORMAD2, which has been implicated in both IBD and T1D and three other T1D candidate genes MTMR3 (protein coding gene), CTA-85E5.10 (processed transcript), CNN2P1 (pseudogene). Two SNPs rs3757247 and rs597325 were located within lncRNA NONHSAG044354 and a protein coding gene BACH2 and a pseudogene RP3-453I5.2. SNP rs602662 was found to be present within antisense lncRNA NONHSAG026183 and protein coding gene FUT2. Strand is displayed in brackets for lncRNAs and their-associated IBD/T1D candidate genes.