Crystal structure of hTEAD2 bound to a methoxypyridine lipid pocket binder
收藏Protein Data Bank Japan2026-03-04 更新2026-04-19 收录
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Crystal structure of hTEAD2 bound to a methoxypyridine lipid pocket binder Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-methoxy-N-({3-[2-(methylamino)-2-oxoethyl]phenyl}methyl)-4-{(E)-2-[trans-4-(trifluoromethyl)cyclohexyl]ethenyl}pyridine-2-carboxamide, Transcriptional enhancer factor TEF-4 Authors: Noland, C.L, Dey, A, Zbieg, J, Crawford, J. Deposit date: 2022-08-10 Release date: 2023-08-16 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation Biorxiv, 2024
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2022-08-10



