A Novel EBF2 Nonsense Variant Drives Adipose Tissue Fibrosis and Dysfunction in Partial Lipodystrophy Syndrome
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE288829
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Heterozygous Ebf2 p.E165X knock-in (KI) mice exhibited restricted adipogenesis and excess extracellular matrix (ECM) deposition during post-weaning AT expansion and high-fat-diet (HFD)-induced obesity. Bulk RNA-seqeuding of inguinal white adipose tissues (IWAT) isolated from 4-week-old wildtype (Ebf2+/+) and knock-in (Ebf2 p.E165X/+) male mice on regular chow diet.
创建时间：
2025-02-17
