Tregs recruited to the omentum and spleen express distinct transcriptomes. Tregs recruited to the omentum and spleen express distinct transcriptomes

To test whether Tregs that were newly recruited to tumor-bearing omentum had similar properties to those of adipose resident Tregs, we surgically joined tumor-bearing mice with congenic naive mice, sorted partner-derived Tregs from the omenta and spleens of tumor-bearing (CD45.1+) parabionts on day 14 and performed RNAseq analysis Overall design: Transcriptomes of Tregs homing to omental tumors and spleen