C3heB/FeJ mice were infected with M. tuberculosis to form necrotic granulomatous lesions. FFPE samples of infected lungs with granulomas were microdissected into three distinct regions, Caseum, foamy

NIAID Data Ecosystem30

Additional file 9: of Metabolic adaptation of two in silico mutants of Mycobacterium tuberculosis during infection

结核病病理

生物系统学

Flux values and shadow prices for all the explored conditions of the icl-mutant and Wildt-type strains. Shadow prices were obtained by dual solution of the FBA while fluxes were obtained by minimizati

Figshare2017-11-21 更新10

Primary topological measures related to directed metabolite-centric networks.

代谢网络推断

有向网络

Primary topological measures related to directed metabolite-centric networks.

NIAID Data Ecosystem50

Table_2_Modeling the Metabolic State of Mycobacterium tuberculosis Upon Infection.DOCX

结核病病理

药物靶点预测

Genome-scale metabolic models of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, have been envisioned as a platform for drug discovery. By systematically probing the networks th

NIAID Data Ecosystem20

Degree values for currency metabolites of Mtb GSMNs.

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