Salivary and mucosal microbiomes of Vietnamese colorectal cancer patients

Dysbiosis in the gut microbiome has been linked to the promotion and prognosis of colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker. Despite the increasing health burden inflicted by CRC in developing countries like Vietnam, the CRC-specific microbiome in these populations remains underexplored. Our study aims to investigate the mucosal microbiome signature and the genomic diversity of Fusobacterium in Vietnamese CRC patients.