aMicroarray array data. bGene expression in wildtype and irr-deficient S. pyogenes strains was determined at both early and late exponential growth phase, indicated by EE and LE resp. Genes that show
aChromosomal locations of start and stop of ChIP-seq peaks. bFold enrichment of PrrA-myc ChIP over control myc antibody ChIP in WT control. cRegulatory role of PrrA on target operons based on change i
For a coherent response to environmental changes, bacterial evolution has formed a complex transcriptional regulatory system comprising classical DNA binding proteins sigma factors and modulation of D
aChomosome coordinate of the ChIP-seq peak in H10407. Underlined text indicates that the ChIP-seq peak maps to sequence that is not conserved in E. coli K-12. bCRP binding site sequence predicted by M
While studying greA expression, we noted presence of an intrinsic terminator in the leader region of greA mRNA transcript. We found this terminator to be quite efficient both in vivo and in vitro. Thi