Inhibitor of MDM2-p53 Interaction
收藏Protein Data Bank Japan2024-05-15 更新2026-03-21 收录
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https://pdbj.org/mine/summary/7biv
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Inhibitor of MDM2-p53 Interaction Descriptor: 1,2-ETHANEDIOL, 6-[[(1~{R})-1-(4-chlorophenyl)-7-fluoranyl-1-[[1-(hydroxymethyl)cyclopropyl]methoxy]-3-oxidanylidene-5-(2-oxidanylpropan-2-yl)isoindol-2-yl]methyl]pyridine-3-carbonitrile, DIMETHYL SULFOXIDE, ... Authors: Williams, P.A. Deposit date: 2021-01-13 Release date: 2021-04-07 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction. J.Med.Chem., 64, 2021
创建时间：
2021-01-13
