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Crystal structure of fms kinase domain with a small molecular inhibitor, PLX5622

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6n33
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Crystal structure of fms kinase domain with a small molecular inhibitor, PLX5622 Descriptor: 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor Authors: Zhang, Y. Deposit date: 2018-11-14 Release date: 2019-09-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model. Nat Commun, 10, 2019
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2018-11-14
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