Crystal structure of PDE8A catalytic domain in complex with 3a
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Crystal structure of PDE8A catalytic domain in complex with 3a Descriptor: 9-[(1~{S})-1-[4-[2,2-bis(fluoranyl)ethoxy]pyridin-2-yl]ethyl]-2-chloranyl-purin-6-amine, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, MAGNESIUM ION, ... Authors: Huang, Y, Wu, X.-N, Zhou, Q, Wu, Y, Luo, H.-B. Deposit date: 2020-08-28 Release date: 2021-09-01 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Rational Design of 2-Chloroadenine Derivatives as Highly Selective Phosphodiesterase 8A Inhibitors. J.Med.Chem., 63, 2020
创建时间：
2020-08-28
