Since loss of the NF2 tumor suppressor gene results in p21-activated kinase (Pak) activation, PAK inhibitors hold promise for the treatment of NF2-deficient tumors. To test this possibility, we asked
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive leukemia of plasmacytoid dendritic cells (pDCs). BPDCN occurs at least three times more frequently in men than women, but the reas
Table S1: HARRIS_HYPOXIA gene set and REACTOME_AUTOPHAGY gene set; Table S2: Hypoxia phenotype score and autophagy phenotype score of each PTC sample in the TCGA-THCA dataset; Table S3: The qPCR prime
Background Oncogenes drive cancer progression, but few are active exclusively in tumor cells. Connexins (Cxs), traditionally recognized as ion channel proteins, can localize to the nucleus and regula
