H5N1 with Mammalian-Adaptive Mutations (HA-Q226L, PB2-T271A) in Germany, 2024 - 2025

This dataset presents nine H5N1 influenza A virus sequences from Germany (Dec 2024 - Apr 2025) carrying mammalian-adaptive mutations HA-Q226L and PB2-T271A, extracted from NCBI surveillance data. Includes full original metadata, mutant sequences, and epidemiological summary (host, location, date). All files shared under CC-BY-4.0 for public health use.This dataset provides molecular evidence of H5N1 evolution with zoonotic risk implications. === H5N1 Germany Surveillance Dataset Summary (v2) ===Generated on: 2025-12-10 19:57:55Source: NCBI Influenza Virus ResourceTotal metadata records: 373Date range: 2024-12-31 — 2025-04-14Host distribution:Gallus gallus: 126Anatidae: 56Meleagris gallopavo: 40Branta leucopsis: 24Mustelidae: 8Cygnus olor: 8 Larus marinus: 8 Chroicocephalus ridibundus: 8 Buteo buteo: 8 Alopochen aegyptiaca: 8 Aves: 8 Ardea cinerea: 8 Canidae: 8 Vulpes vulpes: 8 Anser sp.: 8 Mareca penelope: 8 Branta canadensis: 8 Ciconia ciconia: 8 Anas platyrhynchos: 7Geographic locations (NCBI format): Germany: Germany-NI: 80 Germany: Germany-NW: 61 Germany: Germany-BY: 48 Germany: Germany-TH: 32 Germany: Germany-MV: 32 Germany: Germany-ST: 32 Germany: Germany-SH: 24 Germany: Germany-BB: 24 Germany: Germany-SN: 16 Germany: Germany-BW: 16 Germany: Germany-HE: 8Genotypes observed: H5N1: 373Genomic segments: 1: 47 4: 47 6: 47 5: 47 7: 47 8: 47 2: 46 3: 45Total sequences in FASTA: 373Sequence length range: 225 – 2330 ntPutative segments (from headers): Segment 1: 47 Segment 2: 46 Segment 3: 45 Segment 4: 47 Segment 5: 47 Segment 6: 47 Segment 7: 47 Segment 8: 47Unknown segment count: 0Accessions in metadata: 373Accessions parsed from FASTA headers: 373Matching accessions (intersection): 373Study by: Tahir HB