Transcriptomic study on protective effects of Danhong Injection against cerebral ischemia/reperfusion-induced damage. Transcriptomic study on protective effects of Danhong Injection against cerebral ischemia/reperfusion-induced damage

This study compared the gene expression change of rat brain (cerebral ischemia reperfusion model) before and after Danhong injection treatment Overall design: The Sprague Dawley (SD) rats were subjected to cerebral ischemia reperfusion. After 2 h of occlusion, the nylon suture was pulled out. Animals were Tail vein injected drugs for 14 days after which surgical procedure for the common carotid arteries and reperfusion was performed. Then, the animals that designed to be injected Danhong injection for 14 days. 1. Sham group: sham-operated group 2. Model group:the ischemia-reperfusion group 3. Danhong group:administered with Danhong injection+ ischemia-reperfusion group