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Horning-Crown Macrocycles: Novel Hybrids of Calixarenes and Crown Ethers

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NIAID Data Ecosystem2026-03-06 收录
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Novel macrocycles possessing ether linkages and 2,6-disubstituted phenolics were produced in one step and with 100% atom economy by isoaromatization of chameleon macrocyclic precursors possessing 2,6-diarylidenecyclohexanone moieties. Intramolecular hydrogen bonding of the phenolic hydrogen atoms influenced the shape of the macrocycles and dictated host−guest behavior.

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2016-05-06
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