Survival and Pathways.

The cell cycle stimulatory (CC+) pathway gives additional prognostic information beyond standard clinical covariates such as stage and age, where patients with greater expression levels of the CC+ pathway have an increased hazard compared to those with relative underexpression. The B-cell and EGFR pathways also give additional information where patients with relative overexpression of either of these pathways to better although the relationship with the B-cell pathway only exists in stage 1 patients. In addition, stage 3 patients with relative overexpression of the Notch or the response to hypoxia pathway do worse while stage 2 patients with relative overexpression of pathway representing activity of immunosuppressive interleukins did poorer. Variables not listed were dropped during model selection.