Mutated Mouse P38 MAP Kinase Domain in complex with Inhibitor PG-892579

Mutated Mouse P38 MAP Kinase Domain in complex with Inhibitor PG-892579 Descriptor: 8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM, Mitogen-activated protein kinase 14 Authors: Walter, R.L, Mekel, M.J, Evdokimov, A.G, Pokross, M.E, Sabat, M. Deposit date: 2006-04-28 Release date: 2006-05-23 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production. Bioorg.Med.Chem.Lett., 16, 2006