Adjusted relative risk ratios of each adverse pregnancy outcome relative to live birth in each antenatal diagnostic and drug exposure category compared with no current/past depression or anxiety (512,574 pregnancies in 331,414 women).

aExposures were depression or anxiety with or without exposures to different classes of antidepressants or anti-anxiety drugs. All categories were mutually exclusive.bReference was no history of or current depression or anxiety.cRelative risk ratio after adjusted for maternal age at the end of pregnancy, household socioeconomic status, maternal smoking status before delivery and body mass index before pregnancy.TCAs = tricyclic antidepressants; SSRIs = selective serotonin reuptake inhibitors; CI = confidence interval.