Genes representing 23 attenuated mutants and 1 hypercompetitive mutant when selected in whole porcine blood.

The table lists the mutants that significantly changed in clone number from input to output (pre- and post-selection in whole porcine blood). The top 23 genes represent the mutants that were significantly reduced in number of clones after selection in whole porcine blood. The lowermost gene represents the mutant that significantly increased in clone number after selection in whole porcine blood. Mean read count input and Mean read count output represent the mean number of reads mapping within the defined gene. The differences between the mean values are illustrated by a log fold change from input to output and a negative log2 fold change indicating changes in fitness. A negative log2 fold change defines attenuation in fitness whereas a positive log2 fold change defines increase in fitness. The p-value shows the level of significance.