MAb neutralization of different DENV-1 genotypes.

aNeutralizing activity was determined semi-quantitatively by single endpoint plaque reduction assay on BHK21 or Vero cells with neat hybridoma supernatant cells and 102 PFU of the indicated DENV-1 genotype. The data was derived from at least two independent assays performed in duplicate. Highlighted, italicized values indicate a genotypic specific reduction in neutralizing potential of a given MAb using neat hybridoma supernatant of greater than 20%.