Cryo-EM structure of compound 9n and niacin bound ketone body receptor HCAR2-Gi signaling complex
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Cryo-EM structure of compound 9n and niacin bound ketone body receptor HCAR2-Gi signaling complex Descriptor: 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. Deposit date: 2023-05-26 Release date: 2023-09-06 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation. Mol.Cell, 83, 2023
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2023-05-26
