PLK-1 polo-box domain in complex with a high affinity macrocycle synthesized using a novel glutamic acid analog
收藏Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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PLK-1 polo-box domain in complex with a high affinity macrocycle synthesized using a novel glutamic acid analog Descriptor: ACE-PRO-LEU-ALA-SER-TPO, N-[(4S)-4,5-diamino-5-oxopentyl]-10-phenyldecanamide, Serine/threonine-protein kinase PLK1 Authors: Grant, R.A, Hymel, D, Yaffe, M.B, Burke, T.R. Deposit date: 2021-05-17 Release date: 2022-03-30 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain - binding peptide macrocycles. Org.Biomol.Chem., 19, 2021
创建时间:
2021-05-17



