Supplementary Tables 1-3 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

Supplementary Table S1 contains contingency tables used for Fisher's Exact Test to determine enrichment of binary features in genetic dependency profiles for BRAF, MAPK1 (ERK2), and MAPK3 (ERK1) by BRAFV600 mutation status from three independent screens: DRIVE, ACHILLES, and AVANA. Supplementary Table S2 contains genetic dependency scores for BRAF, MAPK1 (ERK2), and MAPK3 (ERK1) in all BRAF-mutant melanoma cell lines included in three independent screens: DRIVE, ACHILLES, and AVANA. Supplementary Table S3 contains gene set enrichment analysis of RNAseq data from A375 cells with ERK1 or ERK2 knockdown.