Transcriptomic analysis of the follicle associated epithelium of Peyer's Patches, intestinal villous epithelium and ileum from young and aged mice

We have previously shown that aging affects the functional maturation of M cells in the follcile associated epithelium (FAE) of Peyer's patches in the small intestine. To further characterise how aging affects the FAE, mRNA-seq was performed on micro-dissected FAE and villous epithelial sheets as well as whole ileum from young (4 month old) and aged (26-28 month old) mice Overall design: mRNA profiles of follicle associated epithelium of Peyer's Patches (n=3 mice), intestinal villous epithelium (n=4-6 mice) and ileum (n=4 mice) from young and aged mice.