Stereoselective Approach to <i>cis</i>-2,3-Disubstituted Piperidines via Reduction of <i>N</i>‑Acyliminium Ion Intermediate: Enantioselective Synthesis of (+)-(2<i>S</i>,3<i>S</i>)‑CP-99,994
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A very simple and efficient stereoselective approach to cis-2,3-disubstituted piperidines via the reduction of N-acyliminium ion intermediates is described. Application of this methodology is exemplified by the enantioselective total synthesis of (+)-(2S,3S)-CP-99,994.
创建时间:
2016-02-20



