In situ Perturb-seq applied to B16 melanoma tumors
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In situ Perturb-seq is a new method for pooled optical genetic screens with spatial transcriptomics readouts in the intact tissue. Here in situ Perturb-seq was applied to B16 melanoma tumors in immunocompetent mice to investigate top T cell receptor (TCR)-specific immunomodulating hits identified in the melanoma CRISPR activation screens.
创建时间：
2026-02-19
