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Vulliard2021_BioProfilingJl

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Figshare2021-06-22 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Vulliard2021_BioProfilingJl/14784678
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# High-content imaging chemical screen in U-2-OSThis dataset is described in the manuscript untitled "BioProfiling.jl: Profiling biological perturbations with high-content imaging in single cells and heterogeneous populations" by Vulliard _et al_ (DOI: [10.1101/2021.06.18.448961](https://doi.org/10.1101/2021.06.18.448961).The following files are made available:* `README.md`: description of the dataset.* `750CellsPerWell.zip`: raw fluorescent images (TIFF) for a 384-well drug plate seeded with 750 cells per well.* `1500CellsPerWell.zip`: raw fluorescent images (TIFF) for a 384-well drug plate seeded with 1500 cells per well.* `Batch_data_u2os_drug.cpproj`: CellProfiler 3.1.8 pipeline used to analyse the images.* `data.zip`: morphological measurements from CellProfiler per cell for each plate and plate layout. Necessary input to reproduce our [example analyses](https://github.com/menchelab/BioProfilingNotebooks).* `IntermediateResults.zip`: files generated in the [example analyses](https://github.com/menchelab/BioProfilingNotebooks).that are not required but helpful to avoid rerunning all scripts in order.The preparation of the drug plates is described more precisely in the manuscript.
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2021-06-22
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