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Aldesleukin does not achieve a bias in receptor occupancy, regardless of dose or exposure.

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Figshare2017-07-05 更新2026-04-29 收录
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Receptor occupancy of a single dose of NKTR-214 compared to several dosing regimens of aldesleukin, including a theoretical sustained release formulation that provides the same measured AUC as NKTR-214. The values are normalized to the AUC of aldesleukin single dose for each receptor complex.

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2017-07-05
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