Crystal structure of the PDE5A catalytic domain in complex with a novel inhibitor
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Crystal structure of the PDE5A catalytic domain in complex with a novel inhibitor Descriptor: 5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide, MAGNESIUM ION, ZINC ION, ... Authors: Chen, G, Wang, H, Howard, R, Cai, J, Wan, Y, Ke, H. Deposit date: 2007-12-03 Release date: 2008-04-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: An insight into the pharmacophores of phosphodiesterase-5 inhibitors from synthetic and crystal structural studies BIOCHEM.PHARM., 75, 2008
创建时间:
2007-12-03



