UHPLC-MS/MS determination of 15 drugs of abuse and related bioactive metabolites in whole blood: a quick and effective sample pre-treatment procedure and validation of the method

A specific sample pre-treatment procedure was developed in order to improve the reliability of the determination of 15 drugs of abuse and their bioactive metabolites in human whole blood by UHPLC-MS/MS. The shared files contain data and data analysis used for the measurement validation process.