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Expression data from RUNX1S291fs-mutant and/or Ezh2 conditional knockout Lineage-c-Kit+Sca-1+ (LSK) cells

ChEBI2013-09-04 更新2026-07-21 收录

造血干细胞表观遗传学

RUNX1/Ezh2基因功能研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-50537 数据链接链接失效反馈

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资源简介：

Expression data from RUNX1S291fs-mutant and/or Ezh2 conditional knockout Lineage-c-Kit+Sca-1+ (LSK) cells

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创建时间：

2013-09-04

造血干细胞表观遗传学

条件致病性变异

Human genetic variants are classified based on potential pathogenicity to guide clinical decisions. However, mechanistic uncertainties often preclude definitive categorization. Germline coding and enh

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Role of de novo DNA methyltransferases in hematopoietic stem cells (WGBS). Mus musculus

DNA甲基化分析

造血干细胞表观遗传学

To investigate the global DNA methylation changes in Dnmt3a-KO and Dnmt3ab-dKO HSCs compared to control HSCs, we performed whole genome bisulfite sequencing Overall design: Mouse hematopoietic stem ce

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An inflammatory memory of COVID-19 in airway basal stem cells impairs mucociliary differentiation (ATAC-Seq)

造血干细胞表观遗传学

COVID-19研究

Airway basal stem cells (BSCs) in chronic lung diseases accumulate memories to promote disease-specific pathogenesis. Whether acute lung infection also endows BSCs with an inflammatory memory to impai

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Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO)

造血干细胞表观遗传学

白血病发病机制

Aging is associated with functional decline of hematopoietic stem cells (HSC) as well as an increased risk of myeloid malignancies. We performed an integrative characterization of epigenomic and trans

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Spatial genome re-organization between fetal and adult hematopoietic stem cells [RNA-Seq]. Spatial genome re-organization between fetal and adult hematopoietic stem cells [RNA-Seq]

造血干细胞表观遗传学

基因组三维结构重塑

Fetal hematopoietic stem cells (HSCs) undergo a developmental switch to become adult HSCs. The functional properties of the HSCs change dramatically during this switch, including their cycling behavio

NIAID Data Ecosystem30

Expression data from RUNX1S291fs-mutant and/or Ezh2 conditional knockout Lineage-c-Kit+Sca-1+ (LSK) cells

资源简介：

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