Structure of SARS-CoV-2 main protease in complex with a covalent inhibitor

Structure of SARS-CoV-2 main protease in complex with a covalent inhibitor Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase Authors: Greasley, S.E, Ferre, R.A, Liu, W, Stewart, A.E. Deposit date: 2021-07-14 Release date: 2021-11-10 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.729 Å) Cite: An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19. Science, 374, 2021