18 Age-associated hypomethylated open sea blocks enriched for CGIs undergoing age-associated hypermethylation, and containing at least 10 such CGIs.

Columns label chromosome, length of block (Mb), number of contiguous open sea regions defining hypomethylated block, the family wise error rate (FWER) for the hypomethylated block, observed number of age-hyperM CGIs within block, expected number of age-hyperM CGIs within block and Binomial P-value of enrichment of age-hyperM CGIs within block. In bold-face we indicate those significant under adjustment for multiple testing (Benjamini-Hochberg FDR < 0.05). 18 Age-associated hypomethylated open sea blocks enriched for CGIs undergoing age-associated hypermethylation, and containing at least 10 such CGIs.