APOL1-associated kidney disease occurs in some but not all individuals carrying two copies of APOL1 genetic risk variants. The factors leading to kidney disease are incompletely understood. Viral illn

NIAID Data Ecosystem40

Additional file 1 of Modelling APOL1-mediated kidney inflammation and fibrosis using a partially reprogrammed urine-derived SIX2-positive renal progenitor cell line

疾病模型构建

APOL1基因

Supplementary material 1.

DataCite Commons2025-11-13 更新20

Open chromatin, HIF binding and mRNA expression analysis in podocytes (ChIP-Seq).

APOL1基因

HIF-1α信号通路调控

The course of Apolipoprotein 1 (APOL1) nephropathy is extremely heterogeneous and shaped by systemic factors such as the interferon response. However, additional environmental factors operating in a s

NIAID Data Ecosystem20

Additional file 1 of Modelling APOL1-mediated kidney inflammation and fibrosis using a partially reprogrammed urine-derived SIX2-positive renal progenitor cell line

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