KBase

The Department of Energy Systems Biology Knowledgebase (KBase) is a software and data platform designed to meet the grand challenge of systems biology: predicting and designing biological function. KBase integrates data and tools in a unified graphical interface so users do not need to access them from numerous sources or learn multiple systems in order to create and run sophisticated systems biology workflows. Users can perform large-scale analyses and combine multiple lines of evidence to model plant and microbial physiology and community dynamics. KBase is the first large-scale bioinformatics system that enables users to upload their own data, analyze it (along with collaborator and public data), build increasingly realistic models, and share and publish their workflows and conclusions. KBase aims to provide a knowledgebase: an integrated environment where knowledge and insights are created and multiplied.

能源系统生物学知识库（KBase）是一部旨在应对系统生物学领域重大挑战的软件与数据平台，其挑战在于预测与设计生物功能。KBase通过统一的图形界面整合数据与工具，使用户无需从众多来源访问或学习多个系统，即可创建和运行复杂的系统生物学工作流程。用户能够执行大规模分析，并综合多条证据来模拟植物与微生物的生理机能以及群落动态。KBase作为首个大规模生物信息学系统，赋予了用户上传自身数据、分析数据（包括合作者及公共数据）、构建日益逼真的模型、以及共享和发布其工作流程与结论的能力。KBase致力于构建一个知识库：一个集知识创造与累积于一体的集成环境。